Apigenin Powder

What Is Apigenin Explained

Apigenin Powder is an essential raw anti-anxiety material, mainly extracted from the Umbelliferae plant. Apigenin (also known as Versuline) is a bioflavonoid compound (specifically a flavone) that is found in a wide variety of plants and herbs. It is abundant in chamomile tea, and it exerts anxiety-reducing effects when consumed in high doses. At even higher doses, it may be sedative.  Based on the safety and stability of Apigenin, which makes it has been the supplier of hot products, the only can attract customers to buy except the high quality of products; we can also provide purity of not less than 98%Apigenin, if you want to know more information, please contact online with Xi'an Sonwu Biotechnology Co., LTD.

Certificate of Analysis 

 Where To Buy Apigenin

Xi'an Sonwu Biotechnology Co., Ltd. has rich experience in the global trade and health industry. Adhering to integrity-based quality first is the purpose of my company. We strictly control product quality, starting from the selection of raw materials. In addition, we handle every detail to minimize the cost and then provide our customers with more satisfactory service as well as cost-effective products. Based on this, customers have given good feedback on our products. So when purchasing versuline, please choose Xi'an Sonwu Biotechnology Co., Ltd.

Xi'an Sonwu completely makes sure of the product's quality, so samples can be supplied. Here is the quantity.

Customers' Good Comment

OEM Service

Xi'an Sonwu not only can supply pure Apigenin Powder but also supply Apigenin supplement capsules.

So any customers could customize capsules they want. And items below can be supplied.

1.Customized capsules shells (size, color, material)

2.Customized bottles(size, color, material, style)

3.Customized packaging(vacuum foil packaging, box, drum)

4.Customized label(paint film, matte film, optical mask)

What Is The Mechanism of Action of Apigenin

Apigenin (4′, 5, 7-trihydroxy flavone) is a flavone under the category of natural flavonoid that is abundantly present in common fruits, vegetables, nuts, onions, oranges, and tea. Apigenin has various beneficial health effects such as antioxidant, anti-inflammatory, and chemoprevention. Apigenin can downregulate the expression of IL-1β and TNF-α in LPS-stimulated mouse macrophages and human monocytes.56 Apigenin has anti-inflammatory activity by inhibiting COX-2 and iNOS expression in LPS-stimulated mouse macrophages.

Apigenin can suppress inflammatory responses through the inactivation of NF-kappa B. Versuline can attenuate the cellular-mediated inflammatory response by reducing neutrophil and lymphocyte adhesion to endothelial cells. Adhesion of monocytes to HUVECs also occurs by regulating the expression of ICAM and VCAM. In addition, apigenin also inhibits allergen-induced airway inflammation.

These studies suggest that apigenin-mediated anti-inflammatory effects are associated with several intracellular signaling pathways, such as NF-κB, MAPK/ERK, and JNK. Apigenin inhibited LPS-induced IL-1β production by inhibiting caspase-1 activation by disrupting the NLRP3 inflammasome assembly in human THP-1-induced macrophages. It inhibited TNF-α and IL-1β-induced activation of NF-κB, expression of iNOS, NO, COX-2, proinflammatory cytokines, and production of AP-1 proteins. These studies confirm the anti-inflammatory effect of apigenin by inhibiting the expression of inflammatory mediators and AP-1 factors involved in the inflammation and can be used as a potent agent for inflammatory lung disease.

What Are The Health Benefits of Apigenin Supplement

1.Improve sleep quality

Insomnia can profoundly affect your health and well-being. Apigenin has been studied for its ability to improve sleep at night in participants with insomnia not caused by a medication or medical condition. While it only had minimal effects on sleep at night, the participants reported a modest improvement in their ability to function effectively the next day.

2.Control blood sugar levels

Apigenin can help you regulate your blood glucose levels by increasing the amount of insulin you release. This is the hormone that lowers your blood sugar. It can also help prevent some of the health complications of diabetes. Apigenin can help increase the nitric oxide (NO) levels in the cells that make up the walls of your vascular system. In turn, it may protect against damage to your blood vessels when you have diabetes.

3.Anti-anxiety

Apigenin can cross the barrier that separates the blood in your body from the blood in your brain (called the “blood-brain barrier”). This means that it’s able to act on your central nervous system. But using a high content of Apigenin has been shown to have a calming effect. Some studies suggest that Apigenin supplements be helpful for generalized anxiety disorder (GAD). Researchers found that participants reported lower anxiety scores than those who took a placebo.

When Should I Take Apigenin Morning Or Night 

Take one Serving (1 Capsule, 50mg) 30-60 minutes before sleep. Always follow your doctor's advice before taking it.

Generally, consuming Apigenin is considered safe and may even have health benefits. There’s a low risk of toxicity. The amount you eat in your diet is implausible to reach an amount that can cause harm. There is a slightly higher risk of side effects when you intentionally take higher doses of a dietary supplement. The potential side effects of Apigenin are usually mild but can include: Possible allergy to Apigenin-containing foods, Upset stomach, Muscle relaxation Sedation. Make sure to speak with your healthcare provider before taking apigenin supplements if you take any prescription medications.

Factory Environment

Xi'an Sonwu production plant is well-equipped, clean, and tidy, with sufficient stock. Under the leadership of the company, researchers persist in developing new products. The following is the testing environment of our laboratory, advanced testing equipment, and professional testers, with a strict attitude to providing valuable data for our products to provide our customers with a quality experience.

Certificates

Packaging 

Logistics

Why Choose Us

1.Our company has been engaged in import-export for over 10 years and has rich experience in import and export industry.

2.Our company has 10-year experience in product development, production and sales.

3.Our company has a professional team with clear division of labor.

4.We have professional laboratories and equipment to ensure high quality products.

5.Products are tested by third parties.

6.We provide OEM service.

7.We provide 7*24 customer service.

If you want to know the Apigenin Powder price, please get in touch with us online.

E-mail:sales@sonwu.com

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